Haloperidol Decanoate


Haloperidol decanoate has no intrinsic activity. The pharmacological effects are those of haloperidol which is released by bioconversion.The precise mechanism of antipsychotic action is unclear, but is considered to be associated with the potent dopamine D2 receptor blocking activity of haloperidol and the resulting adaptive changes in the brain. Haloperidol is also a potent antagonist of opiate receptors, and has weak antagonist activity at muscarinic, histamine H1, alpha-adrenergic, and serotonin receptors (Dollery 1991).

indications
Anti - Psychotic

specifications
BP/Ph. Eur.

regulatory status
DMF

Therapeutic Focus
Neurology

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